Identification of potential metabolite markers for colon cancer and rectal cancer using serum metabolomics

Staging of colorectal cancer using serum metabolomics with 1HNMR Spectroscopy

Objective(s): Determination of stages of colon cancer is done by biopsy usually after surgery. Metabolomics is the study of all the metabolites using LC-MS and 1HNMR spectroscopy with chemometric techniques. The stages of colon cancer were detected from patients' sera using 1HNMR. Materials and Methods: Five ml blood was collected from 16 confirmed patients referred for colonoscopy.  One group ...

Serum Metabolomics and Liver Cancer Title: Serum Metabolomics and Liver Cancer Translational Relevance Serum Metabolomics and Liver Cancer

1 Purpose: Metabolomics depicts metabolic changes in biological systems using a 2 multiparametric analysis technique. This study assessed the metabolomic profiles of 3 serum, obtained by proton NMR spectroscopy, from cirrhotic patients with and without 4 hepatocellular carcinoma (HCC). Experimental Design: The study included 154 5 consecutive patients with compensated biopsy-proven alcoholic ci...

Screening For Colon and Rectal Cancer.

Robotic Surgery for Colon and Rectal Cancer

Robotic surgery, used generally for colorectal cancer, has the advantages of a three-dimensional surgical view, steadiness, and seven degrees of robotic arms. However, there are disadvantages, such as a decreased sense of touch, extra time needed to dock the robotic cart, and high cost. Robotic surgery is performed using various techniques, with or without laparoscopic surgery. Because the resu...

Laparoscopic surgery for colon and rectal cancer.

Laparoscopic techniques are now being applied to increasing numbers of general surgical procedures. Technical feasibility, margins, number of lymph nodes, and recurrence rates need to be assessed with the application of this new technique to colon or rectal malignancies. Technically, the right colon, sigmoid, and proximal rectum appear to be the most amenable to laparoscopic assisted or complet...